Best Way to Plan a trip to Asia

[Innocent Bystander]

Caveat: no sex tourism

Advice required:
- best tours
- worst tours
- best housing option
- car, bike or boat
- best time of year
- how much money to bring
- medical
- plumbing
- how long to plan to take during the trip
- how not to piss off the locals/become a statistic
- legal differences

Thank you.